Chao MA
Contact：mcpumc@163.com
Education
1991-1999 Peking Union Medical College, M.D.
Academic Experience
2019-present Director, National Human Brain Bank for Development and Function
2015-present Dean of Medial Education, Peking Union Medical College.
2011-present Professor and Chair, Department of Anatomy, Histology and Embryology, Institute of Basic Medical Sciences, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.
2008-2011 Assistant Professor, Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA.
2003-2008 Associate Research Scientist, Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA.
2000-2003 Postdoctoral Associate, Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA.
1999-2000 Resident Surgeon, Department of Surgery, Peking Union Medical College Hospital, Beijing, China.
Overview of Academic Research
1. Establishment of the National Human Brain Bank for Development and Function, the Standardized Operational Protocol for Human Brain Banking in China, and the China Human Brain Banking Consortium;
2. Investigation of the mechanisms and therapeutic strategy of neurodegenerative diseases, including the neuropathological characteristics of human brain aging and Alzheimer’s Disease;
3. Study on the neuro-immunological mechanisms of chronic pain and development of novel analgesics.
Major Honor and Awards
“PUMC Scholar”, Peking Union Medical College & Chinese Academy of Medical Sciences, 2011
“Young Anatomical Scientist in China”, Chinese Society of Anatomical Sciences, 2016
“Beijing Brain Scholar”, Chinese Institute for Brain Research, Beijing 2020
National Award in Education, 2018; National Award in Excellent Course, 2020
Representative Research Achievements
1. Qiu W, Zhang H, Bao A, Zhu K, Huang Y, Yan X, Zhang J, Zhong C, Shen Y, Zhou J, Zheng X, Zhang L, Shu Y, Tang B, Zhang Z, Wang G, Zhou R, Sun B, Gong C, Duan S, Ma C*. Standardized Operational Protocol for Human Brain Banking in China. Neurosci Bull. 35(2):270-276, 2019.
2. Xiong F, Ge W*, Ma C*. Quantitative proteomics reveals distinct composition of amyloid plaques in Alzheimer's disease. Alzheimer's & Dementia 15(3):429–440, 2019.
3. Wang W, Wang M, Yang M, Zeng B, Qiu W, Ma Q, Jing X, Zhang Q, Wang B, Yin C, Zhang J, Ge Y, Liu Y, Ji W, Wu Q*, Ma C*, Wang X*. Transcriptome dynamics of hippocampal neurogenesis in macaques across the lifespan and aged humans. Cell Res 32:729-743, 2022.
4. Liu F, Sun J, Wang X, Jin S, Sun F, Wang T, Yuan B, Qiu W, Ma C*. Focal-but not diffuse-type Amyloid beta plaques are correlated with Alzheimer’s neuropathology, cognitive dysfunction and neuroinflammation in the human hippocampus. Neurosci Bull 38:1125-1138, 2022.
5. Liu F, Zhang L, Su S, Fang Y, Yin X-S, Cui H, Sun J, Xie Y, Ma C*. Neuronal C-reactive protein/FcγRI positive feedback proinflammatory signaling contributes to nerve injury-induced neuropathic pain. Advanced Science 2023.
6. Liu F, Shen X, Su S, Cui H, Fang Y Wang T, Zhang L, Huang Y, Ma C*. FcγRI-coupled signaling in peripheral nociceptors mediates joint pain in a rat model of rheumatoid arthritis. Arthritis Rheumatol 72(10):1668-78, 2020.
7. He Y, Qin L, Fang Y, Dan Z, Shen Y, Tan G, Huang Y*, Ma C*. Electrospun PLGA Nanomembrane: A Novel Formulation of Extended- Release Bupivacaine Delivery Reducing Postoperative Pain. Materials & Design 193:108768, 2020.
8. Jiang H, Shen X, Chen Z, Liu F, Wang T, Xie Y, Ma C*. Nociceptive Neuronal Fc-gamma receptor I is involved in IgG immune complex induced pain in the rat. Brain Behav Immun 62:351-361, 2017.
9. Qu L, Li Y, Pan X, Zhang P, LaMotte RH, and Ma C*. Transient Receptor Potential Canonical 3 (TRPC3) Is Required for IgG Immune Complex-Induced Excitation of the Rat Dorsal Root Ganglion Neurons. J Neurosci 32(28):9554-62, 2012.